The Benzo Bends

This article explores the potential problems with long-term use of anti-anxiety medication and the importance of re-humanising the treatment of emotional distress. The original article, published in the Irish Examiner can be read here

 

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By Liz Dunphy

Every morning Carmel wakes up from a fitful, toxic sleep in her Tipperary home. Her whole body vibrates like an internal jackhammer is belting her from inside — a loud sharp tinnitus floods her brain with distracting noise, her muscles forget how to function and her skin feels too tight for her body.

These are just some of the symptoms that have plagued Carmel for 19 long months since she stopped taking low daily doses of Valium which she was prescribed since August 2007.

Valium (or diazepam) is a benzodiazepine, a drug mostly used to treat anxiety disorders and muscle spasms. Benzodiazepines enhance the effect of the brain’s tranquilising neurotransmitter GABA which slows down over-activity to reduce symptoms of anxiety.

Many others could be experiencing Carmel’s painful and isolating withdrawal symptoms in Ireland today. The 2012 HSE PCRS report which lists the 100 medications most frequently prescribed to medical card patients ranked diazepam as the 26th most prescribed drug in Ireland, having dropped one place in Ireland’s drug popularity stakes from 25th place in 2011.

There is no official data on how frequently private prescriptions for benzodiazepines are issued, but Minister Kathleen Lynch says benzodiazepines are being excessively prescribed.

“We have to take a serious look at prescribing practices across the whole Department of Health, the problem is not just limited to psychiatric illnesses,” says Minister Lynch.

Ivor Browne is Professor Emeritus of Psychiatry at UCD, he was the Chief Psychiatrist of the Eastern Health Board and he is an eminent author on mental health.

Browne believes that benzodiazepines can be useful for relieving temporary anxiety but they should not be used on any regular or long-term basis because they are habit-forming.

“Anything that removes anxiety will be potentially addictive,” says Browne.

“Valium or its generic form Anxicalm can be effective, but all of these drugs are grossly overused, the person experiencing difficulties must work to overcome the traumas they have suffered with the support of a therapist.

“Psychotherapy, when it’s effectively undertaken, is the only real therapy. And Prozac and all other SSRIs (Selective Serotonin Reuptake Inhibitors, used as antidepressants) are actually dangerous and in my opinion should never be used,” says Browne.

“Everything is disconnected in our society when everything in reality is interconnected, this needs to change to solve our societal problems.

“We need to recognise that the heart is our real centre, not the brain. All our emotional life is centred in the heart and there are more messages going from the heart to the brain than vice-versa. There’s an awful lot yet to be understood,” says Browne.

Prof David Healy is the Professor of Psychopharmacology at Bangor University in Wales, he is Irish and his innovative website www.RxISK.org  invites people to research and report the benefits and side effects experienced when using prescription drugs. People can record their experiences on the website which will generate a free RxISK report that they can bring to their own doctor.

The gathered accounts form a database that aims to make medicine safer for patients. Healy believes it can also help to equalise power between doctors and patients by giving patients an option to record their symptoms with other medical professionals for free. And Healy believes that equalising that power is vital to improving our healthcare system.

“In the 1960s drugs were viewed as poisons. The magic of medicine was that doctors could use poison to produce good. Industry has changed this model, turning pharmaceuticals into something to be used as a fertiliser, to be sprinkled widely, but these drugs are generally tested on people for four to six weeks, not for the months or years that people are actually prescribed them for.

“The human body can take poisons for a month — but not for indefinite, constant periods of time without doing damage,” says Healy.

Bridget Hayes, a mother of three is from Limerick, she was prescribed Xanax for 20 years to treat anxiety which began when she experienced thyroid problems.

“I feel like I’ve lost 20 years of my life. I was turned into an addict. I went to hospital as a day patient for years and no one said that I shouldn’t be on all these medications for so long, no one ever mentioned that they could be addictive either,” says Hayes.

“And they never offered counselling, even though they had a psychotherapist in that hospital. They just dish out tablets, and there are obviously reasons why people feel anxious or depressed which they need to talk about and understand. Psychotherapy should be the first port of call for these problems.”

Echoing concerns voiced by Prof Healy and Prof Browne about the additional dangers of SSRIs, Hayes noted that when an SSRI called Seroxat was added to her drug cocktail things got even worse.

“On Seroxat I lost all emotion, I couldn’t feel anything and I didn’t care about anyone, least of all myself. I had never had depression before but this anti-depressant made me feel suicidal. I started drinking heavily and I tried to kill myself a few times.”

Hayes realised that the medication was making her worse, and asked to stop.

“Dr Terry Lynch saved me. I read his book Beyond Prozac and I recognised myself in it. I started the Ashton method with Dr Lynch to come off Xanax, he taught me coping strategies and he’s a huge support,” says Hayes.

The Ashton method is a protocol for benzodiazepine withdrawal developed by Professor Heather Ashton, an Emeritus Professor of Clinical Psycho-pharmacology at the University of Newcastle upon Tyne, England, in which you slowly reduce your dose while managing your symptoms. The Ashton Manual, which includes tapering schedules, is available on www.benzo.org.uk

“Once I came off Xanax and only took small doses of Valium I suddenly regained feelings and memories,” says Hayes. “My parents died a few years ago but I cried over their deaths for the first time recently, I had been so numbed by medication that I couldn’t feel any emotions.”

Hayes still has good and bad days but she has learned coping mechanisms, like deep breathing to deal with anxiety without medication.

“I feel cheated from so many years of my life. I have to go through hell to get off the medication and the people who put me on it can’t help me. The receptors in my brain are still damaged from the medication and it will take time to heal,” says Hayes.

“And it’s such a contradiction, these drugs are known to cause depression and anxiety as a side effect, yet people are prescribed them to treat those very symptoms.”

Dr Terry Lynch who helped Hayes with her benzodiazepine withdrawal, practiced as a GP before noticing problems in how medicine addressed mental health issues. He writes books on the topic (including a best seller Beyond Prozac, and a new book Depression Delusion, Vol.

One: The Myth of the Brain Chemical Imbalance, published this month). He now works full time helping people to improve their mental health through a combination of emotional, psychological and physical interventions, including medication.

“The existence of brain chemical imbalances, which psychiatric drugs are supposedly designed to correct, has never been scientifically verified. It’s a widely promoted and accepted myth. The pain and distress are very real but the chemical imbalance is not.

“These problems need to be addressed from a broader perspective, one that includes the emotional and psychological aspects of the person as well as the physical.

“The starting point should be seeking to make sense of people’s experiences and emotions at a human level,” says Lynch.

“Generally the medical profession now accept that benzodiazepines can be addictive and can cause difficult withdrawal symptoms but that awareness came belatedly.”

Lynch is concerned that a similarly delayed recognition of the potential problems with SSRIs may be currently unfolding. “As a society, we need to reconsider whether a biologically-dominated model for emotional and mental health and wellbeing is best for people or not,” he says.

Unexpected journeys can begin in the most mundane of ways. Mary*, a young mother from Tipperary fell off a slide while on holiday when holding her four-year-old on her lap.

“I got burning nerve pains after the fall, I thought that I had a degenerative neurological disease and I got quite depressed. My GP gave me an anti-depressant called sertraline (a SSRI), Xanax (alprazolam — a benzodiazepine) and the sleeping pill zopiclone ( a Z drug that works in a very similar way to benzodiazepines).

“Four weeks later I experienced severe, deep twitching in my legs and I still had burning nerve pains. I went to see a consultant who prescribed amitriptyline which worked well and ended my nerve pain, but afterwards I was hospitalised for tachycardia, which was actually quite lucky because the hospital diagnosed drug-induced arrhythmia, so I knew then that the medication was causing problems.”

Mary* only took the medication for six weeks but she has battled withdrawal symptoms for 13 months. “I asked to come off the medication and I didn’t crave it at all but my body and brain just couldn’t adapt quickly to functioning without them. But my cousin took them for three to four months and stopped taking them with no problems, so we all react differently,” says Mary*.

“I found that my symptoms matched the benzodiazepine withdrawal symptoms others reported on the internet. I learned that certain substances, like sugar and alcohol really aggravated my symptoms because they excite the nervous system, and MSG is a neurotoxin anyway so this worsens my symptoms too.

“Once I had information I felt more in control of what was happening. But Baylissa Frederick really saved me, she set up great online resources http://www.RecoveryRoad.org and a counselling website http://www.baylissa.co.uk. Without Baylissa’s help and support I’d either be on a very hard, painful, lonely road or else I’d be dead.”

Baylissa Frederick, the woman that Mary* attributes with helping her to cope with withdrawal, was first prescribed the benzodiazepine clonazepam in early 1998 for dystonia, a movement disorder.

“I didn’t know the drug was addictive until I started feeling unwell, I exhausted diagnostic tests and had multiple emergency visits to casualty, before I found the Ashton Manual online.”

“Of all the people I’ve supported, 90% found out the drug was the cause of their problems via the internet and asked their doctors to come off it. They print off tapering schedules from the Ashton Manual to bring to their doctors.

“For those on the drug who plan to stop taking it, never stop abruptly. Speak to your doctor and find a tapering schedule that is safe and not rushed.”

Frederick believes that normal emotions such as grief and stress are now pathologised.

Instead of allowing people to process these feelings and deal with them through talking and human support, people visit their GPs and end up with a prescription to a drug that could potentially cause them further problems.

“Many of the people I support were put on benzos, z-drugs and antidepressants for normal reactions to grief. At first I was shocked at how many had become dependent on these meds because of a bereavement,” says Frederick.

“Benzodiazepines basically put a chemical cushion between you and reality,” says Dr John Dunphy, a GP in Carrigaline, Co Cork, “that cushion can be very useful if you hit a rocky patch that is too uncomfortable to bear temporarily — but the problem is that that cushion can also smother you if it’s not closely monitored.”

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Natural Cure for Depression, Bipolar, ADHD, Schizophrenia..

Abram Hoffer PhD, RNCP, President Orthomolecular Vitamin Information Centre speaks about treating mental health concerns with nutrients. This alternative therapy employs vitamins, minerals, and amino acids to create optimum nutritional content for the body, as well as the right environment and equilibrium. Like most alternative medicine techniques, orthomolecular medicine targets a wide range of conditions. [depression, bipolar, adhd, schizophrenia, add, addiction, alcoholism, drug addiction…]

Orthomolecular medicine was developed by Linus Pauling, Ph.D., winner of two Nobel prizes, in 1968. It is designed to enable individuals to reach the apex of health and the peak of their performance by utilizing only naturally occurring substances (e.g. vitamins, minerals, enzymes, trace elements, co-enzymes). The proper balance of these substances in the body is the key to reaching physical, mental, and emotional health and stability. Orthomolecular medicine can be used therapeutically to treat diseases such as cancer and AIDS, or preventatively to impede the progress of degenerative disease and aging. When all is said and done, however, the main objective of orthomolecular medicine is to help the patient reach an optimal level of health; his or her self-esteem will probably improve in the process.

Although orthomolecular medicine did not fully develop into a therapy until the late 1960’s when Pauling coined the term “orthomolecular,” the premise behind this practice originated in the 1920’s, when vitamins and minerals were first used to treat illnesses unrelated to nutrient deficiency. It was discovered that vitamin A could prevent childhood deaths from infectious illness, and that heart arrhythmia (irregular heartbeat) could be stopped by dosages of magnesium. Hard scientific evidence supporting nutritional therapy did not emerge, however, until the 1950’s, when Abram Hoffer, M.D., and Humphrey Osmond, M.D., began treating schizophrenics with high doses of vitamin B3 (niacin). As a consequence of their studies, it was revealed that niacin, in combination with other medical treatments, could double the number of recoveries in a one-year period.

Eventually, it was determined that malnutrition and consumption of refined, empty-calorie foods such as white bread and pastries and overconsumption of sugar could yield disease and psychiatric disorders. It became apparent that a person’s diet was an overwhelmingly integral part of his or her health and well-being. Further studies showed that decreased intake of dietary fiber, bran, minerals, and complex carbohydrates was prevalent in patients with certain forms of mental illness, accompanied by a loss of vitamins and an increase in dietary fat.

Biochemical individual is a main principle of orthomolecular medicine. This principle was elucidated by Roger J. Williams, Ph.D. This principle is quite simple: every living organism is unique! Furthermore, each individual requires different relative amounts of nutrients for his or her satisfaction and optimal level of health. The government sets a minimum recommended daily allowance (RDA) which is supposed to be adequate for all individuals. However, many may need to exceed the RDA as well as the recommended 2,000 calorie diet in order to prevent severe deficiency disease. Thus, RDA values are not perfect guidelines for everyone. Several studies have proven the existence of biochemical individuality. For example, studies of guinea pigs showed a twentyfold variation in their requirement for vitamin C. A study conducted with human subjects revealed that children have varying needs for vitamin B6.

http://www.orthomolecularvitamincentr…
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